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Merck

F6397

Sigma-Aldrich

IgG1−FITC Isotype Control from murine myeloma

clone MOPC 21, purified immunoglobulin, buffered aqueous solution

Sinónimos:

IgG1 Isotype Control from murine myeloma

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

mouse

Nivel de calidad

conjugado

FITC conjugate

forma del anticuerpo

purified immunoglobulin

clon

MOPC 21, monoclonal

Formulario

buffered aqueous solution

condiciones de almacenamiento

protect from light

técnicas

flow cytometry: suitable

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

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Descripción general

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.

Aplicación

IgG1-FITC Isotype Control from murine myeloma was used as negative control in FACS of human erythroid cell population that is expresses CD17.
IgG1?FITC Isotype Control from murine myeloma has been used in flow cytometry and as a negative staining control.

Acciones bioquímicas o fisiológicas

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) plays a major role in hypersensitivity type II and type III reactions. IgG is also involved in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Nota de preparación

Prepared by conjugation to fluorescein isothiocyanate isomer I (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development
Seeberger H, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 81(7), 977-977 (2001)
Murat O Arcasoy et al.
British journal of haematology, 130(1), 121-129 (2005-06-29)
The regeneration of circulating red blood cells in response to anaemia associated with blood loss or haemolysis involves an increased rate of erythropoiesis and expansion of proerythroblasts, the bone marrow precursor cells that terminally differentiate into mature erythrocytes. This study
The Laboratory Rat (1998)
The Immunoglobulins: Structure and Function (1998)
Molecular Genetics of Immunoglobulin, 17 (1987)

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