F1428

Fenvalerate

≥97%

• Sinónimos: α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)­iso­valerate
• Fórmula empírica (notación de Hill): C₂₅H₂₂ClNO₃
• Número de CAS: 51630-58-1
• Peso molecular: 419.90
• Beilstein: 2025982
• Número MDL: MFCD00055324
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329799681
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• Análisis: ≥97%
• temp. de almacenamiento: −20°C
• cadena SMILES: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• Clave InChI: NYPJDWWKZLNGGM-UHFFFAOYSA-N

Descripción

Descripción general

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

Aplicación

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

Acciones bioquímicas o fisiológicas

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Piretroide de tipo II. Potente inhibidor de la calcineurina (proteína fosfatasa 2B).

Nota de preparación

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H301,H315,H319,H335,H410
• Consejos de prudencia: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable