E8031

Esmolol hydrochloride

≥98% (HPLC), solid

• Sinónimos: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride
• Fórmula empírica (notación de Hill): C₁₆H₂₆NClO₄
• Número de CAS: 81161-17-3
• Peso molecular: 331.83
• Número MDL: MFCD00941432
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329799075
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥98% (HPLC)
• formulario: solid
• condiciones de almacenamiento: desiccated
• mp: 89.0-90.6 °C
• solubilidad: H₂O: 12 mg/mL
• emisor: Baxter
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1
• InChI: 1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
• Clave InChI: GEKNCWBANDDJJL-UHFFFAOYSA-N
• Información sobre el gen: human ... ADRB1(153) , ADRB2(154)

Descripción

Aplicación

Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.

Acciones bioquímicas o fisiológicas

Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.

Esmolol hydrochloride is a ultrashort-acting β₁ adrenoceptor antagonist (β₁ receptor occupancy = 84.7%).

Características y beneficios

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves