C8645

Cinoxacin

• Sinónimos: 1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
• Fórmula empírica (notación de Hill): C₁₂H₁₀N₂O₅
• CAS Number: 28657-80-9
• Peso molecular: 262.22
• Número CE: 249-133-8
• Número MDL: MFCD00056776
• Código UNSPSC: 51102829
• ID de la sustancia en PubChem: 24278343
• NACRES: NA.85

Propiedades

• Formulario: powder or crystals
• Nivel de calidad: 200
• espectro de actividad antibiótica: Gram-negative bacteria
• Modo de acción: DNA synthesis | interferes; enzyme | inhibits
• cadena SMILES: CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12
• InChI: 1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)
• Clave InChI: VDUWPHTZYNWKRN-UHFFFAOYSA-N

Descripción

Descripción general

Chemical structure: quinolone

Aplicación

Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes.

Acciones bioquímicas o fisiológicas

Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp.

Otras notas

Keep container tightly closed in a dry and well-ventilated place.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)