C4963
Catalase−polyethylene glycol
lyophilized powder, ~40,000 units/mg protein
Sinónimos:
PEG-Catalase
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About This Item
Productos recomendados
formulario
lyophilized powder
Nivel de calidad
actividad específica
~40,000 units/mg protein
mol peso
PEG 5,000
composición
Protein, ~50% E405
Extensión del etiquetado
~40 mol PEG per mol protein
unión a la matriz
secondary amine linkage.
temp. de almacenamiento
−20°C
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Aplicación
Pulmonary artery endothelial cells treated with PEG-catalase showed effective inhibition of 20- HETE (hydroxyeicosatetraenoic acid)-induced increase in fluorescence. However, the experiment excludes potential nonspecific fluorescence of DCF (dichlorofluorescein). This experiment studied the effect of 20-HETE on superoxide production and NADPH oxidase activation.
Acciones bioquímicas o fisiológicas
Catalase from bovine liver catalyzes the decomposition of H2O2 into water and oxygen. It is a tetramer consisting of four equal subunits with a molecular weight of 60 kDa each. Each subunit contains iron bound to a protoheme IX group. The enzyme also strongly binds NADP, which is in close proximity to the heme group. Catalase activity is constant over the pH range of 4.0-8.5. The pI is found to be 5.4. The enzyme activity is inhibited by 3-amino-1-H-1,2,4 triazole, cyanide, azide, hydroxylamine, cyanogen bromide, 2-mercaptoethanol, dithiothreitol, dianisidine, and nitrate. Incubation of catalase with ascorbate or ascorbate/Cu2+ results in degradation of the catalase molecule. It does not require any activators.
Envase
Package size based on protein content
Otras notas
Catalase from bovine liver coupled to methoxy-polyethylene glycol.
Forma física
Contains PEG plus 5% citrate buffer salts
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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