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B7688

Sigma-Aldrich

PiB

≥98% (HPLC)

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About This Item

Fórmula empírica (notación de Hill):
C22H18N2O8
Número de CAS:
64005-90-9
Peso molecular:
438.39
Número MDL:
MFCD00333607
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329773301
NACRES:
NA.77

Nivel de calidad

100

Análisis

≥98% (HPLC)

formulario

powder

color

white to light brown

solubilidad

DMSO: 1-2 mg/mL (warmed)

temp. de almacenamiento

2-8°C

cadena SMILES

O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O

InChI

1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3

Clave InChI

WNKQGFNIIHNGQM-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Thioflavine S practical grade

Sigma-Aldrich

T1892

Thioflavine S

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To assess in a longitudinal study whether subjective cognitive decline (SCD) and brain β-amyloid (Aβ) contribute unique information to cognitive decline. One hundred thirty-six healthy elderly from the Berkeley Aging Cohort Study were followed up for a mean of 4
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