A9736

A-438079 hydrochloride hydrate

≥98% (HPLC)

• Sinónimos: 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate
• Fórmula empírica (notación de Hill): C₁₃H₉Cl₂N₅·HCl · xH₂O
• Número de CAS: 899431-18-6
• Peso molecular: 342.61 (anhydrous basis)
• Número MDL: MFCD17215929
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329771058
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• condiciones de almacenamiento: desiccated
• color: white to beige
• solubilidad: DMSO: 20 mg/mL, clear
• emisor: Abbott
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3
• InChI: 1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2
• Clave InChI: ZHFJJBAKSROKNO-UHFFFAOYSA-N

Descripción

Aplicación

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

Acciones bioquímicas o fisiológicas

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Características y beneficios

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable