A3785

5-Aminolevulinic acid hydrochloride

≥98%, suitable for ligand binding assays

• Sinónimos: δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
• Fórmula lineal: NH₂CH₂C(O)CH₂CH₂COOH · HCl
• Número de CAS: 5451-09-2
• Peso molecular: 167.59
• Beilstein: 3690651
• Número CE: 226-679-5
• Número MDL: MFCD00012869
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24890811
• NACRES: NA.26

Propiedades

• Nombre del producto: 5-Aminolevulinic acid hydrochloride, ≥98%
• Nivel de calidad: 300
• Ensayo: ≥98%
• Formulario: powder
• técnicas: ligand binding assay: suitable
• mp: 150 °C
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl[H].NCC(=O)CCC(O)=O
• InChI: 1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
• Clave InChI: ZLHFONARZHCSET-UHFFFAOYSA-N

Descripción

Aplicación

5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy for A431 tumor bearing mice.

Acciones bioquímicas o fisiológicas

5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget′s disease and HPV infection-associated cervical condylomata acuminata.

Intermediate in heme biosynthesis.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable