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Merck

A3293

Sigma-Aldrich

Anti-Human Albumin antibody produced in rabbit

whole antiserum

Sinónimos:

Albumin Antibody, Albumin Antibody - Anti-Human Albumin antibody produced in rabbit, Anti Human Albumin Antibody

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

rabbit

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

whole antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

mol peso

antigen 66.437-66.6 kDa

contiene

15 mM sodium azide

reactividad de especies

human

técnicas

indirect ELISA: 1:60,000
quantitative precipitin assay: 2.4-3.6

Nº de acceso UniProt

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ALB(213)

Descripción general

Albumin′s primary structure is composed of a single chain of amino acids and the secondary structure is composed of α-helix of six turns and 17 disulfide bridges. The tertiary structure is 3D and is composed of three domains I II and III. Each of these domains are made of sub-domains IAB, IC, IIAB, IIC, IIIAB, IIIC, respectively.

Especificidad

Anti-human albumin antibodies are specific for human albumin.

Inmunógeno

Human albumin

Aplicación

Anti-Human Albumin antibody has been used in enzyme linked immunosorbent assay (ELISA) and in immobilization of antibodies for human serum albumin (HSA).
Anti-human albumin antibody may be used in quantitative precipitin assay, high-throughput protein microarray analysis and immunocytochemistry .
Rat hepatocytes were grown on collagen-coated coverslips, fixed in formalin and permeablized with methanol prior to incubation with rabbit anti-human albumin antibody.

Acciones bioquímicas o fisiológicas

Albumin is a transport protein that binds a broad range of ligands such as fatty acids, bilirubin, hemin, drugs, amino acids and ions among several others . Albumin may also function as a zinc carrier protein and consequently regulate physiological processes .
Albumin plays a major role in transportation and deposition of many exogenous and endogenous substances in blood.

Forma física

Supplied as a liquid containing 15mM sodium azide as preservative.

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Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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The analysis and characterisation of immuno-unreactive urinary albumin in healthy volunteers
Clavant S P, et al.
Clinical Biochemistry, 39(2), 143-151 (2006)
Interaction of bovine (BSA) and human (HSA) serum albumins with ionic surfactants: spectroscopy and modelling
Gelamo E L, et al.
Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology, 1594(1), 84-99 (2002)
Yi Luo et al.
The Journal of pharmacology and experimental therapeutics, 321(3), 884-891 (2007-03-21)
Epidermal growth factor (EGF) stimulation of cell cycle progression in cultured primary hepatocytes has previously been reported to be dependent on the mammalian target of rapamycin (mTOR) elements of the phosphoinositide 3-kinase (PI3K) signaling cascade and not the Akt pathway.
Real-time multianalyte biosensors based on interference-free multichannel monolithic quartz crystal microbalance
Jaruwongrungsee K, et al.
Biosensors And Bioelectronics, 67, 576-581 (2015)
Tien T Le et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 241(3), 493-504 (2012-01-26)
During vertebrate lens development, the lens placode in the embryonic ectoderm invaginates into a lens vesicle, which then separates from the surface epithelium, followed by two waves of fiber cell differentiation. In the mouse, multiple labs have shown that Jag1-Notch

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