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A2504

Sigma-Aldrich

6-Aminocaproic acid

≥99% (titration), powder

Sinónimos:

ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA

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About This Item

Fórmula lineal:
H2N(CH2)5CO2H
Número de CAS:
60-32-2
Peso molecular:
131.17
Beilstein:
906872
Número CE:
200-469-3
Número MDL:
MFCD00008238
Código UNSPSC:
12352202
ID de la sustancia en PubChem:
24890662
NACRES:
NA.77

origen biológico

synthetic

Nivel de calidad

300

Análisis

≥99% (titration)

formulario

powder

técnicas

cell culture | mammalian: suitable

color

white

mp

207-209 °C (dec.) (lit.)

solubilidad

H2O: 50 mg/mL

cadena SMILES

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

Clave InChI

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Información sobre el gen

human ... PLAT(5327) , PLG(5340)
rat ... Ppm1a(24666)

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Aplicación

EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.

Acciones bioquímicas o fisiológicas

EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo­xy­peptidase, plasmin, and plasminogen activator.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

404.6 - 408.2 °F

Punto de inflamabilidad (°C)

207 - 209 °C

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

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