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94259

Sigma-Aldrich

(±)-Mevalonic acid 5-pyrophosphate tetralithium salt

≥80% (qNMR)

Sinónimos:

(±)-MVAPP, (±)-Mevalonic acid 5-diphosphate tetralithium salt

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About This Item

Fórmula empírica (notación de Hill):
C6H10Li4O10P2
Número de CAS:
108869-00-7
Peso molecular:
331.85
Número MDL:
MFCD16875404
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
329770318
NACRES:
NA.25

Análisis

≥80% (qNMR)

formulario

powder

color

white

temp. de almacenamiento

−20°C

cadena SMILES

[Li+].[Li+].[Li+].[Li+].CC(O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O

InChI

1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4

Clave InChI

GFIXUUFXTAPBAD-UHFFFAOYSA-J

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Acciones bioquímicas o fisiológicas

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase. Mevalonic acid 5-pyrophosphate was shown to elevate ubiquinone levels in rat liver tissues.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile metabolites are simultaneously extracted with good recoveries into 7 M urea at neutral pH
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Isoprenoids are a very diverse family of organic compounds widespread in the three domains of life. Although they are produced from the condensation of the same precursors in all organisms (isopentenyl pyrophosphate and dimethylallyl diphosphate), the evolutionary origin of their
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