80198

Methoxatin disodium salt

≥97.0% (HPLC)

• Sinónimos: PQQ, Pyrrolo-quinoline-quinone disodium salt
• Fórmula empírica (notación de Hill): C₁₄H₄N₂Na₂O₈
• Número de CAS: 122628-50-6
• Peso molecular: 374.17
• Número MDL: MFCD00151711
• Código UNSPSC: 12352005
• ID de la sustancia en PubChem: 329768729
• NACRES: NA.79

Propiedades

• origen biológico: fermentation/recombinant
• Nivel de calidad: 100
• Ensayo: ≥97.0% (HPLC)
• Formulario: powder
• color: red-brown to deep orange; red-brown to deep red-brown
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
• InChI: 1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
• Clave InChI: UFVBOGYDCJNLPM-UHFFFAOYSA-L

Descripción

Descripción general

Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

Aplicación

• Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).

Acciones bioquímicas o fisiológicas

In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)