62962

L-α-Lysophosphatidylcholine

egg yolk, ≥99.0% (TLC)

• Sinónimos: 3-sn-Lysophosphatidylcholine, L-α-Lysolecithin
• Número MDL: MFCD00131444
• Código UNSPSC: 51321705
• NACRES: NA.25

Propiedades

• origen biológico: egg yolk
• descripción: zwitterionic
• Análisis: ≥99.0% (TLC)
• formulario: powder or solid
• composición: 16:0, ~69% (fatty acid); 18:0, ~27% (fatty acid); 18:1, ~3% (fatty acid)
• solubilidad: chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow
• grupo funcional: phospholipid
• tipo de lípido: phosphoglycerides
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C

Descripción

Aplicación

• The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).


• Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).

Acciones bioquímicas o fisiológicas

3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .

Otras notas

Preparation of demembranated frog sperm chromatin

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)