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Merck
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Key Documents

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61251

Sigma-Aldrich

Palmitoyl-L-carnitine

≥97.0% (HPLC)

Sinónimos:

(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium inner salt, L-Carnitine hexadecanoyl ester, C16-Carnitine, Hexadecanoyl-L-carnitine

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About This Item

Fórmula empírica (notación de Hill):
C23H45NO4
Número de CAS:
2364-67-2
Peso molecular:
399.61
Beilstein:
4152034
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
329759410
NACRES:
NA.26

Nivel de calidad

100

Análisis

≥97.0% (HPLC)

actividad óptica

[α]/D -17±2°, c = 1 in methanol

impurezas

≤10% water

temp. de almacenamiento

2-8°C

cadena SMILES

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1

Clave InChI

XOMRRQXKHMYMOC-OAQYLSRUSA-N

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Acciones bioquímicas o fisiológicas

L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Margaret-Ann M Nelson et al.
Amino acids, 51(1), 97-102 (2018-09-08)
Oxidative deamination of norepinephrine (NE) and dopamine (DA) by monoamine oxidase (MAO) generates the catecholaldehydes 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL) and 3,4-dihydroxyphenylacetaldehyde (DOPAL), respectively, and H2O2. Catecholaldehydes are highly reactive electrophiles that have been implicated as causal factors in the etiology of neurodegenerative
Stephanie J Mihalik et al.
Obesity (Silver Spring, Md.), 18(9), 1695-1700 (2010-01-30)
Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating FAO defects in vivo in humans has entailed complex and invasive methodologies. Recently, the identification of genetic blocks in
Sanne J C M Frambach et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(6), 165727-165727 (2020-02-20)
Mitochondrial complex I (CI), the first multiprotein enzyme complex of the OXPHOS system, executes a major role in cellular ATP generation. Consequently, dysfunction of this complex has been linked to inherited metabolic disorders, including Leigh disease (LD), an often fatal
Katherine A Overmyer et al.
Cell metabolism, 21(3), 468-478 (2015-03-05)
Maximal exercise-associated oxidative capacity is strongly correlated with health and longevity in humans. Rats selectively bred for high running capacity (HCR) have improved metabolic health and are longer-lived than their low-capacity counterparts (LCR). Using metabolomic and proteomic profiling, we show
Sang Hoon Lee et al.
Journal of controlled release : official journal of the Controlled Release Society, 311-312, 74-84 (2019-09-06)
This research aimed to develop a pH-responsive organic-inorganic hybrid nanocomposite as an effective oral delivery system for protein drugs. Three different nanocomposites were prepared by using bovine serum albumin (BSA) as a model protein. A nanocomplex of BSA with 3-aminopropyl
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