468R-1

Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP417, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (468R-14); vial of 0.1 mL concentrate Research Use Only (468R-14-RUO); vial of 0.5 mL concentrate (468R-15); vial of 1.0 mL concentrate (468R-16); vial of 1.0 mL concentrate Research Use Only (468R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (468R-17); vial of 7.0 mL pre-dilute ready-to-use (468R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO)
• fabricante / nombre comercial: Cell Marque^™
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• isotipo: IgG
• control: lung adenocarcinoma
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: membranous
• Información sobre el gen: human ... CLDN4(1364)

Descripción

Descripción general

The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.¹ In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.² Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.³ Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.⁴ Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.^5,6

Calidad

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

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Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2