465R-1

TROP2 (EP431) Rabbit Monoclonal Primary Antibody

• Sinónimos: Trophoblast Antigen 2
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP431, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (465R-14); vial of 0.1 mL concentrate Research Use Only (465R-14-RUO); vial of 0.5 mL concentrate (465R-15); vial of 1.0 mL concentrate (465R-16); vial of 1.0 mL concentrate Research Use Only (465R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (465R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (465R-17); vial of 7.0 mL pre-dilute ready-to-use (465R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (465R-18-RUO)
• fabricante / nombre comercial: Cell Marque^™
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotipo: IgG
• control: papillary carcinoma of thyroid
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic, membranous
• Información sobre el gen: human ... TACSTD2(4070)

Descripción

Descripción general

Trophoblast antigen 2 (TROP2) is a transmembrane glycoprotein that transduces intracellular calcium signals. The overexpression of TROP2 has been linked to tumor progression due to its involvement in the regulation of multiple vital cell processes including migration, proliferation, and invasion. TROP2 exhibits strong, diffuse staining in papillary thyroid carcinoma, while staining in other thyroid lesions, such as follicular thyroid adenomas and carcinomas, is limited to rare, focal, or scattered cells. An increase in TROP2 expression has also been observed in colorectal carcinomas and ovarian serous carcinomas compared to non-neoplastic ovary and colon.

Calidad

IVD

IVD

IVD

RUO

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

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Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2