426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

• Sinónimos: Signal Transducer and Activator of Transcription
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP325, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (426R-14); vial of 0.1 mL concentrate Research Use Only (426R-14-RUO); vial of 0.5 mL concentrate (426R-15); vial of 1.0 mL concentrate (426R-16); vial of 1.0 mL concentrate Research Use Only (426R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (426R-17); vial of 7.0 mL pre-dilute ready-to-use (426R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)
• fabricante / nombre comercial: Cell Marque^™
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotipo: IgG
• control: solitary fibrous tumor
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: nuclear
• Información sobre el gen: human ... STAT6(6778)

Descripción

Descripción general

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Calidad

IVD

IVD

IVD

RUO

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable