40674

Pinoresinol

≥95.0% (HPLC)

• Sinónimos: (+)-Pinoresinol, 4,4′-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol), 4,4′-[(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxyphenol)
• Fórmula empírica (notación de Hill): C₂₀H₂₂O₆
• Número de CAS: 487-36-5
• Peso molecular: 358.39
• Número MDL: MFCD07784516
• Código UNSPSC: 12352205
• ID de la sustancia en PubChem: 329756010
• NACRES: NA.25

Propiedades

• Análisis: ≥95.0% (HPLC)
• formulario: powder or crystals
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• cadena SMILES: COc1cc(ccc1O)[C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c4ccc(O)c(OC)c4
• InChI: 1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
• Clave InChI: HGXBRUKMWQGOIE-AFHBHXEDSA-N

Descripción

Descripción general

Pinoresinol is a secondary metabolite, a lignan found in wide varieties of plants. Structurally, it is one of the simple lignans, with a dimer of coniferyl alcohol, which forms the bicyclic ring core.

Aplicación

Pinoresinol has been used:

• as a reference standard for qualitative and quantitative analysis of lignans from Triticale (X Triticosecale Wittmack) grains using ultra-performance liquid chromatography (UPLC) with photodiode and mass TQD detectors
• as an enterolignan precursor to study its estrogenic activity on the proliferation of human breast cancer MCF-7 cells
• as a reference standard for lignan analysis of Sesamum indicum L. seeds

Acciones bioquímicas o fisiológicas

Pinoresinol is present in a number of plants including medical plants like Sambucus williamsii, Eucommia ulmoides (duzhong), Styrax sp, Forsythia suspensa, and in extra virgin olive oil. The genus Sambucus is widely distributed in Europe, Asia, and North Africa, and has been used in traditional medicine as an analgesic, antivirus, antiinflammatory, homoeostatic, and diuretic drugs which act on bruises, fractures, and edema. Pinoresinol displays potent antifungal properties by causing damage to the fungal plasma membrane. It exerts anti-oxidative and anti-inflammatory activities by inhibition of TNF- α production (presumably through inhibition of NF- κB and AP-1).

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable