360R-1

Hemoglobin A (EPR3608) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EPR3608, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (360R-14); vial of 0.5 mL concentrate (360R-15); bottle of 1.0 mL predilute (360R-17); vial of 1.0 mL concentrate (360R-16); bottle of 7.0 mL predilute (360R-18)
• fabricante / nombre comercial: Cell Marque^™
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• isotipo: IgG
• control: bone marrow, placenta
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic

Descripción

Descripción general

Hemoglobin alpha chain belongs to the globin family and is involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin A is comprised of two alpha chains and two beta chains, whereas hemoglobin A2 is comprised of two alpha chains and two delta chains. Immunohistochemical localization of hemoglobin is excellent as an erythroid marker for the detection of immature, dysplastic, and megaloblastic erythroid cells in myeloproliferative disorders, such as erythroleukemia. In contrast, myeloid cells, lymphoid cells, plasma cells, histiocytes, and megakaryocytes stain negative with anti-hemoglobin A. Anti-hemoglobin A, combined with antibodies against CD34, CD117, CD68, and MPO can be helpful in distinguishing between reactive extramedullary hematopoiesis and that seen in neoplastic myeloid disorders in spleen. Anti-hemoglobin A is limited to expression by erythroid precursors in bone marrow and is therefore of assistance in calculating percentages of erythroid precursors.

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

HEMOGLOBIN A Positive Control Slides, Product No. 360S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable