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Merck
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337M-8

Sigma-Aldrich

TAG-72 (B72.3) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

B72.3, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (337M-84)
vial of 0.5 mL concentrate (337M-85)
bottle of 1.0 mL predilute (337M-87)
vial of 1.0 mL concentrate (337M-86)
bottle of 7.0 mL predilute (337M-88)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG1κ

control

lung adenocarcinoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Descripción general

Anti-B72.3 recognizes a high molecular weight glycoprotein called TAG-72 that is present in human adenocarcinomas and in lesser amounts, non-neoplastic tissues. It has also been found to be useful to distinguish between mesothelioma and adenocarcinoma, however, false positive reactions can occur so results must be interpreted with the utmost caution.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

TAG-72 Positive Control Slides, Product No. 337S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificados de análisis (COA)

Lot/Batch Number
0000290785
0000290785
1416311A-Z

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T S Kline et al.
Cancer, 63(11), 2253-2256 (1989-06-01)
Monoclonal antibody B72.3 (MoAb B72.3) is a potentially valuable diagnostic adjunct when applied to aspiration biopsy cytology (ABC). In this prospective study, its reactivity was tested on the ABC from 25 breast lesions interpreted as suspicious. The stain was applied
W W Johnston et al.
Human pathology, 17(5), 501-513 (1986-05-01)
Monoclonal antibody B72.3 has been shown to be reactive with a high-molecular-weight glycoprotein complex termed TAG(tumor-associated glycoprotein)-72. By the avidin-biotin immunoperoxidase method, fine needle aspirates and corresponding surgically excised tumor tissues from both malignant and benign tissues were analyzed for
David C Chhieng et al.
Human pathology, 34(10), 1016-1021 (2003-11-11)
Ovarian carcinoma has a high mortality rate, because most ovarian carcinomas are detected at a late stage. Traditional therapies, such as surgical debulking and chemotherapy, have not been successful in improving the long-term survival of these patients. Alternative therapies targeting
A Thor et al.
Cancer research, 46(6), 3118-3124 (1986-06-01)
Murine monoclonal antibody B72.3, prepared against a membrane-enriched extract of human metastatic carcinoma, was reacted with a spectrum of adult and fetal human tissues using avidin-biotin-complex immunohistochemical techniques to evaluate the expression of the reactive tumor associated glycoprotein (TAG)-72 antigen.
The use of Mab B72.3 in the diagnosis of human carcinoma
Schlom J, et al.
J. Tumor Marker oncol., 2, 95-112 (1987)
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