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Key Documents

336R-1

Sigma-Aldrich

Synaptophysin (EP158) Rabbit Monoclonal Primary Antibody

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About This Item

Código UNSPSC:
12352203

origen biológico

rabbit

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

EP158, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (336R-14)
vial of 0.1 mL concentrate Research Use Only (336R-14-RUO)
vial of 0.5 mL concentrate (336R-15)
vial of 1.0 mL concentrate (336R-16)
vial of 1.0 mL concentrate Research Use Only (336R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (336R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (336R-17)
vial of 7.0 mL pre-dilute ready-to-use (336R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (336R-18-RUO)

fabricante / nombre comercial

Cell Marque

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

isotipo

IgG

control

pancreas (islet cells)

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... SYP(6855)

Descripción general

Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

Synaptophysin Positive Control Slides, Product No. 336S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

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Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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M Skacel et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(3), 203-209 (2000-09-12)
Histologic differential diagnosis of acinar cell carcinoma (ACC), mixed acinar-endocrine cell carcinoma (MAEC), and pancreatic endocrine tumors (PET) can be difficult but is important because of differences in their clinical behavior. This study investigates the utility of immunohistochemistry (IHC) in
Eun-Ik Son et al.
Pathology international, 53(2), 67-73 (2003-02-18)
Medulloblastomas occurring in children represent a histological spectrum of varying anaplasia and nodularity. In order to determine whether immunohistochemical markers might be useful parameters in subclassifying these tumors, 17 pediatric medulloblastomas, including nine diffuse/non-anaplastic, four diffuse/anaplastic, three nodular/non-anaplastic and one
K Kayser et al.
Pathology, research and practice, 183(4), 412-417 (1988-08-01)
The value of immunoreactivity of antibodies against neuronspecific enolase (NSE), bombesin (GRP), and synaptophysin (SY 38) as markers for various human lung carcinoma has been assessed. One hundred-forty-two primary bronchus carcinomas (small cell anaplastic carcinoma, epidermoid carcinoma, adeno carcinoma, and
T Kamisawa et al.
Pathology, research and practice, 192(9), 901-908 (1996-09-01)
To evaluate the significance of neuroendocrine differentiation in duct carcinoma of the pancreas, we investigated 79 pancreatic carcinomas, applying histochemistry and immunohistochemistry (chromogranin A, Leu-7, synaptophysin and neuron-specific enolase (NSE), and correlated the morphologic differentiation pattern with clinicopathological characteristics. There
M H Lyda et al.
Human pathology, 31(8), 980-987 (2000-09-15)
The histologic classification of pulmonary neoplasms can have important implications regarding appropriate management of patients. Although the histologic classification of lung tumors is predominantly based on morphology, ancillary studies such as immunohistochemistry can be used in difficult cases, and the

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