30891

Biliverdin hydrochloride

≥97.0% (TLC)

• Sinónimos: Biliverdin
• Fórmula empírica (notación de Hill): C₃₃H₃₄N₄O₆ · HCl
• Número de CAS: 856699-18-8
• Peso molecular: 619.11
• Código UNSPSC: 12352204
• ID de la sustancia en PubChem: 329753599
• NACRES: NA.32

Propiedades

• Análisis: ≥97.0% (TLC)
• formulario: powder or crystals
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl.CC1=C(C=C)C(\NC1=O)=C\c2[nH]c(/C=C3\N=C(\C=C4/NC(=O)C(C=C)=C4C)C(C)=C3CCC(O)=O)c(CCC(O)=O)c2C
• InChI: 1S/C33H34N4O6.ClH/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26;/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41);1H/b26-13-,27-14-,28-15-;
• Clave InChI: KTRFJVRKVQROKS-UJCZHUFNSA-N

Descripción

Descripción general

Biliverdin (BV) is considered as a near-infrared (NIR)-absorbing pigment, that is endogenic. It is a linear tetrapyrrolic intermediate of heme degradation (heme catabolism) to bilirubin. The bile of amphibia and birds contains only biliverdine, no bilirubin.

Aplicación

Biliverdin hydrochloride has been used:

• as a treatment to J774A.1 cells to study its role in alternation of beta (β)-endorphins level
• as a commercial standard for the detection of biliverdin in mouse unstable and stable plaques tissues using liquid chromatography-tandem mass spectrometry (LC-MS-MS)
• to add to Fucci-containing cells to improve the mIFP signal
• to examine its impact on infrared fluorescent protein (iRFP) in some retinal preparations

Acciones bioquímicas o fisiológicas

Biliverdin (BV) is an excellent anti-inflammatory agent that protects against lipopolysaccharides (LPS)-induced lung injury in mouse endothelial cells. It aids protection in polymicrobial sepsis. Biliverdin has cytoprotective effects on rat livers and protects from prolonged ischemia and reperfusion injury. It also shows antioxidant activities.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable