259R-1

Glucagon (EP74) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP74, monoclonal
• descripción: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: bottle of 1.0 mL predilute (259R-17); bottle of 7.0 mL predilute (259R-18); vial of 0.1 mL concentrate (259R-14); vial of 0.5 mL concentrate (259R-15); vial of 1.0 mL concentrate (259R-16)
• fabricante / nombre comercial: Cell Marque^™
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
• isotipo: IgG
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: human ... GCG(2641)

Descripción

Descripción general

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon.¹ Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome² (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.³ Immunohistochemically, the two types of glucagonomas are reactive to the glucagon antibody, though occasionally only weakly.

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

Glucagon Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable