100-05A

Human Dermal Microvascular Endothelial Cells: CADMEC/HMVEC, adult

• Código UNSPSC: 41106514
• NACRES: NA.81

Propiedades

• origen biológico: human neonatal foreskin or adult skin capillaries (normal)
• Nivel de calidad: 100
• envase: pkg of 500,000 cells
• fabricante / nombre comercial: Cell Applications, Inc
• modo de crecimiento: Adherent
• cariotipo: 2n = 46
• morfología: Endothelial
• técnicas: cell culture | mammalian: suitable
• Condiciones de envío: dry ice
• temp. de almacenamiento: −196°C

Descripción

Descripción general

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CADMEC/HMVEC provide an excellent model system to study many aspects of endothelial function and disease, especially those related to the microvasculature and capillary systems. HMVEC/CADMEC have been shown to express vWF, CD36 and CD31, are able to uptake DiI-Ac-LDL and are positive for functional activity by cytokine-stimulated leukocyte adherence.

Select HMVEC lots have been additionally tested to demonstrate stimulation-dependent angiogenesis and key endothelial cell signaling pathways (phosphorylation of VEGFR, Akt, MAPK, and expression of Tie2, eNOS, Axl and Etk/Bmx).

Origen línea celular

Skin

Aplicación

Endothelial vessel function, cell signaling, angiogenesis

Componentes

Cell Basal Medium containing 10% FBS & 10% DMSO

Nota de preparación

• 2nd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Rutina de subcultivo

Please refer to the CADMEC/HMVEC Culture Protocol.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable