09278

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester

≥98.0% (HPLC)

• Sinónimos: 4-(Dimethylamino)azobenzene-4′-carboxylic acid N-succinimidyl ester, DABCYL-N-succinimidyl ester
• Fórmula empírica (notación de Hill): C₁₉H₁₈N₄O₄
• Número de CAS: 146998-31-4
• Peso molecular: 366.37
• Número MDL: MFCD00467415
• Código UNSPSC: 12352108
• ID de la sustancia en PubChem: 329748752
• NACRES: NA.32

Propiedades

• Nivel de calidad: 100
• Análisis: ≥98.0% (HPLC)
• formulario: powder
• solubilidad: DMF: soluble; DMSO: soluble
• fluorescencia: λ_ex 428 nm; λ_em 453 nm
• temp. de almacenamiento: −20°C
• cadena SMILES: CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)C(=O)ON3C(=O)CCC3=O
• InChI: 1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3/b21-20+
• Clave InChI: IBOVDNBDQHYNJI-QZQOTICOSA-N

Descripción

Aplicación

A useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies.

Nota de análisis

Absorption spectra shows a maximum at 453 nm (in methanol). After reaction with butylamine: max. absorption at 428 nm (Lit.)

Otras notas

N-terminal modification of peptides in automated synthesis

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)