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S0883

Sigma-Aldrich

Sulfasalazine

97.0-101.5%

Sinónimos:

2-Hydroxy-5-{{4-[(2-pyridinylamino)sulfonyl]phenyl}azo}benzoic acid, 5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic acid, Salicylazosulfapyridine

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About This Item

Fórmula empírica (notación de Hill):
C18H14N4O5S
Número de CAS:
599-79-1
Peso molecular:
398.39
Beilstein:
356241
Número CE:
209-974-3
Número MDL:
MFCD00057363
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329824182
NACRES:
NA.24

Nivel de calidad

200

Análisis

97.0-101.5%

formulario

powder

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

260-265 °C (dec.) (lit.)

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)

Modo de acción

DNA synthesis | interferes
enzyme | inhibits

cadena SMILES

OC(=O)c1cc(ccc1O)\N=N\c2ccc(cc2)S(=O)(=O)Nc3ccccn3

InChI

1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+

Clave InChI

NCEXYHBECQHGNR-QZQOTICOSA-N

Información sobre el gen

human ... ALOX5(240) , PTGS1(5742) , PTGS2(5743)

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Descripción general

Chemical structure: sulfonamide
Sulfasalazine (SSZ) belongs to the sulfonamide class of drugs, which can be metabolized into 5-aminosalicylic acid and sulfapyridine. SSZ is obtained as a reaction product of an antibacterial agent (sulfapyridine) and an anti-inflammatory agent (salicylic acid).

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfasalazine has been used as an analytical standard in clinical studies:
  • For investigating its therapeutic potential in patients suffering from multiple sclerosis (MS).
  • For studying its role as an antiarthritic agent via inhibition of the cartilage degeneration and pain associated with progression of osteoarthritis in the rat, which is used as the test animal.

It may also be used as an analytical reference standard for the quantification of the analyte in biological samples and aqueous samples using enzyme-linked immunosorbent assay (ELISA) and spectrofluorimetic technique.



Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palabra de señalización

Danger

Frases de peligro

H317,H334,H351,H361f,H411

Clasificaciones de peligro

Aquatic Chronic 2 - Carc. 2 - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
029M4794V
019M4892V
019M4773V
078M4898V
048M4826V

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Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

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