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Key Documents

PHR2021

Supelco

Candesartan Cilexetil Related Compound G

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Candesartan, 1-{[2′-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid(Candesartan Cilexetil Related Compound G), 2-Ethoxy 1-{[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}benzimidazole-7-carboxylic acid

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About This Item

Fórmula empírica (notación de Hill):
C24H20N6O3
Número de CAS:
Peso molecular:
440.45
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to USP 1087870

familia API

candesartan

CofA

current certificate can be downloaded

envase

pkg of 20 mg

aplicaciones

pharmaceutical

formato

neat

temp. de almacenamiento

2-8°C

InChI

1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

Clave InChI

HTQMVQVXFRQIKW-UHFFFAOYSA-N

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Descripción general

Candesartan Cilexetil Related Compound G is an impurity of candesartan cilexetil (CAN), which is classified as an angiotensin II receptor antagonist. CAN finds application in the treatment of hypertension, and can be used in cardiac patients with impaired left ventricular systolic function. It is a pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

CAN may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB6842 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazard

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Repr. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

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Tools for early prediction of drug loading in lipid-based formulations
Alska?r LC, et al.
Molecular Pharmaceutics, 13(1), 251-261 (2015)
New simple spectrophotometric method for determination of the binary mixtures (atorvastatin calcium and ezetimibe; candesartan cilexetil and hydrochlorothiazide) in tablets
Belal T, et al.
Journal of Pharmaceutical Analysis, 3(2), 118-126 (2013)

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