PHR1890

Tiotropium bromide monohydrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Fórmula empírica (notación de Hill): C₁₉H₂₂BrNO₄S₂ · H₂O
• Número de CAS: 139404-48-1
• Peso molecular: 490.43
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. Y0001188
• familia API: tiotropium
• CofA: current certificate can be downloaded
• envase: pkg of 50 mg
• aplicaciones: pharmaceutical
• formato: neat
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C19H22NO4S2.BrH.H2O/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H;1H2/q+1;;/p-1/t11?,12-,13+,16-,17+;;
• Clave InChI: MQLXPRBEAHBZTK-KFEMZTBUSA-M

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Tiotropium bromide monohydrate is structurally related to ipratropium bromide. It is a second-generation anticholinergic agent specific for muscarinic receptors (M1, M2 & M3) in humans.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Tiotropium bromide monohydrate may be used as a reference compound to investigate the role of M2 and M3 muscarinic receptors in the contraction of rat and human small airways.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB0347 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable