PHR1768

Dexamethasone Sodium Phosphate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Dexamethasone 21-phosphate disodium salt, 9-Fluoro-11b,17, 21-trihydroxy-16α- methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) disodium salt
• Fórmula empírica (notación de Hill): C₂₂H₂₈FNa₂O₈P
• Número de CAS: 2392-39-4
• Peso molecular: 516.40
• Beilstein: 6473066
• Número CE: 219-243-0
• Número MDL: MFCD00079105
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823600
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to BP 108; traceable to Ph. Eur. D0720000; traceable to USP 1177032
• familia API: dexamethasone
• CofA: current certificate can be downloaded
• envase: pkg of 1 g
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O
• InChI: 1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1
• Clave InChI: PLCQGRYPOISRTQ-FCJDYXGNSA-L
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

Dexamethasone is a glucocorticoid and an anti-inflammatory agent, widely used in ocular inflammatory diseases.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Dexamethasone Sodium Phosphate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using differential pulse polarography technique and high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC1690 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302,H361d
• Consejos de prudencia: P201 - P301 + P312 + P330 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Oral - Repr. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable