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PHR1427

Supelco

Glycolic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Glycolic acid, Hydroxyacetic acid

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About This Item

Fórmula lineal:
HOCH2COOH
Número de CAS:
79-14-1
Peso molecular:
76.05
Beilstein:
1209322
Número CE:
201-180-5
Número MDL:
MFCD00004312
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329822593
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

300

familia API

glycolic acid

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

75-80 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

Clave InChI

AEMRFAOFKBGASW-UHFFFAOYSA-N

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Descripción general

Glycolic acid is an α-hydroxy acid with exfoliating and anti-ageing properties. It is useful in dermatology, medical, cosmetics, and pharmaceutical applications.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Glycolic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography (GC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC3641 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

CorrosionExclamation mark
GHS05,GHS07

Palabra de señalización

Danger

Frases de peligro

H314,H332

Clasificaciones de peligro

Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

>572.0 °F - (decomposition)

Punto de inflamabilidad (°C)

> 300 °C - (decomposition)

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Applications of hydroxy acids: classification, mechanisms, and photoactivity
Kornhauser A, et al.
Clinical, cosmetic and investigational dermatology, 3, 135?142-135?142 (2010)
Glycolic Acid
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 35(6), 6168-6168 (2013)
Rongcai Liang et al.
Pharmaceutical research, 31(8), 1958-1966 (2014-02-20)
To prepare acylated exenatide analogues and investigate their biological properties for guiding the development of PLGA formulations of exenatide. The acylated exenatide analogues were prepared by reaction with glycolic acid (GA), one constitutional unit of PLGA, and characterized by HPLC-MS/MS
A D Katsambas
Dermatology (Basel, Switzerland), 210 Suppl 1, 39-45 (2005-02-23)
Acne vulgaris affects 3 out of 4 adolescents and usually vanishes at the end of puberty with either no sequelae or mild to moderate sequelae, such as postinflammatory hyperpigmenation (PIH), which may result in psychological and emotional damages. The poor
H Murad et al.
Dermatologic clinics, 13(2), 285-307 (1995-04-01)
Glycolic acid is a member of the AHA family, which occurs naturally in foods and has been used for centuries as a cutaneous rejuvenation treatment. Recently it has proved to be a versatile peeling agent and it is now widely
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