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Merck

PHR1424

Supelco

Ampicilina sodium salt

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

D-(−)-α-Aminobencilpenicilina sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C16H18N3NaO4S
Número de CAS:
Peso molecular:
371.39
Beilstein:
4119211
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to BP 785
traceable to Ph. Eur. A1000000
traceable to USP 1033203

familia API

ampicillin

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

215 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1

Clave InChI

KLOHDWPABZXLGI-YWUHCJSESA-M

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Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Ampicillin Sodium may be used as a pharmaceutical secondary reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography with ultra violet detection and second-derivative spectrophotometry, respectively.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Modo de acción: Es un antibiótico ß-lactámico que inhibe la síntesis de la pared celular bacteriana al inactivar las transpeptidasas de la superficie interna de la membrana celular de la bacteria.

Modo de resistencia: La administración con ß-lactamasa rompe el anillo ß-lactámico de la ampicilina y la inactiva.

Espectro antimicrobiano: Incluye bacterias grampositivas (como la bencilpenicilina) y baterías gramnegativas (como las tetraciclinas y el cloranfenicol).

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA2732 in the slot below. This is an example certificate only and may not be the lot that you receive.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazard

Palabra de señalización

Danger

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Protocolos

USP HPLC Analysis of Ampicillin Sodium on Ascentis® Express C18

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