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Merck

PHR1423

Supelco

Sodium Nitroprusside

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Sodium nitroferricyanide(III) dihydrate, Nitroprusside sodium, SNP, Sodium nitroprusside, Sodium pentacyanonitrosylferrate

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About This Item

Fórmula lineal:
Na2[Fe(CN)5NO] · 2H2O
Número de CAS:
Peso molecular:
297.95
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to USP 1614501

familia API

sodium nitroprusside

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[Na+].[Na+].[H]O[H].[H]O[H].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

Clave InChI

OIRZWVYIQXBRFC-UHFFFAOYSA-N

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Descripción general

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Sodium Nitroprusside is widely used as a drug to manage hypertension, via lowering elevated blood pressure by acting on the arteriolar smooth muscle.

Aplicación

Sodium Nitroprusside may be used as a spectrophotometric reagent for the analysis of meloxicam in pharmaceutical formulations using spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB7818 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Precios

Pictogramas

Skull and crossbones

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Antihypertensive Drugs (1997)
Spectrophotometric determination of meloxicam by sodium nitroprusside and 1, 10-phenanthroline reagents in bulk and its pharmaceutical formulation
Gurupadayya MB, et al.
Indian Journal of Chemical Technology, 20, 111-115 (2013)
Laura A E Cox et al.
Shock (Augusta, Ga.), 43(4), 322-326 (2015-01-08)
Although endothelial dysfunction is central to the pathogenesis of sepsis, no specific and clinically applicable marker for endothelial dysfunction is currently available. Endocan, a proteoglycan excreted by endothelial cells in response to inflammatory cytokines, may serve as such a marker.
Oliver Baretella et al.
Life sciences, 118(2), 206-212 (2014-01-15)
Levels of the endothelium-derived peptide endothelin-1 (ET-1) are elevated in obese humans, and ET-1 mediated vascular tone is increased. Renal arterial smooth muscle is highly responsive to ET-1. Whether or not endothelium-derived ET-1 affects contractions of the renal artery under
Gary J Hodges et al.
Experimental physiology, 99(2), 381-392 (2013-11-12)
What is the central question of this study? Previous work has produced the counterintuitive finding that the vasoconstrictor neurotransmitters noradrenaline and neuropeptide Y are involved in vasodilatation. We aimed to discover whether sympathetic neurotransmitters are required for the sustained vasodilatation

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