PHR1366

Dibutyl phthalate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Dibutyl phthalate, n-Butyl phthalate, DBP, Phthalic acid dibutyl ester
• Fórmula lineal: C₆H₄-1,2-[CO₂(CH₂)₃CH₃]₂
• Número de CAS: 84-74-2
• Peso molecular: 278.34
• Beilstein: 1914064
• Número CE: 201-557-4
• Número MDL: MFCD00009441
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823345
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. D1010000; traceable to USP 1187080
• densidad de vapor: 9.6 (vs air)
• presión de vapor: 1 mmHg ( 147 °C)
• familia API: dibutyl phthalate
• CofA: current certificate can be downloaded
• temp. de autoignición: 756 °F
• lim. expl.: 0.47 %, 236 °F
• envase: pkg of 1 g
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• índice de refracción: n20/D 1.492 (lit.)
• bp: 340 °C (lit.)
• mp: −35 °C (lit.)
• densidad: 1.043 g/mL at 25 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: CCCCOC(=O)c1ccccc1C(=O)OCCCC
• InChI: 1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
• Clave InChI: DOIRQSBPFJWKBE-UHFFFAOYSA-N

Descripción

Descripción general

Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol. It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Plasticizer

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• Pictogramas: GHS08,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H360FD,H410
• Consejos de prudencia: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Clasificaciones de peligro: Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 339.8 °F
• Punto de inflamabilidad (°C): 171 °C