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Merck

PHR1093

Supelco

Sulfanilamide

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Sulfanilamide, p-Aminobenzenesulfonamide

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About This Item

Fórmula lineal:
H2NC6H4SO2NH2
Número de CAS:
Peso molecular:
172.20
Beilstein:
511852
Número CE:
Número MDL:
Código UNSPSC:
41116107
eCl@ss:
39093202
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to USP 1633007

familia API

sulfanilamide

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

~Approximately 166 °C
164-166 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

Clave InChI

FDDDEECHVMSUSB-UHFFFAOYSA-N

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Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfanilamide Melting Point Standard, also called Sulfanilamide, is an antibacterial drug. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Sulfanilamide Melting Point Standard also called Sulfanilamide is an antibacterial drug.

Aplicación

It was used in a study to demonstrate photodecomposition in aqueous solution of cutaneous photosensitizing agents with the help of spin traps 5, 5-dimethyl-1-pyrroline-1-oxide.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB1410 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

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Visite la Librería de documentos

SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS?II. SPIN TRAPPING OF PHOTOLYSIS PRODUCTS FROM SULFANILAMIDE AND 4-AMINOBENZOIC ACID USING 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE.
Chignell, Colin F., et al.
Photochemistry and Photobiology, 34.2 , 147-156 (1981)
Xian-Long Wang et al.
European journal of medicinal chemistry, 45(10), 4631-4639 (2010-08-17)
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal
Fei Liu et al.
Organic letters, 12(4), 868-871 (2010-01-19)
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of
Ramazan Demirdağ et al.
Bioorganic & medicinal chemistry, 21(6), 1522-1525 (2012-09-15)
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold with a yield of 60.75%, and a specific activity of
Sevgi Kolayli et al.
Journal of enzyme inhibition and medicinal chemistry, 26(6), 895-900 (2011-03-09)
An α-carbonic anhydrase (CA, EC 4.2.1.1) was purified and characterized kinetically from erythrocytes of the sturgeon Acipenser gueldenstaedti, an endangered species. The sturgeon enzyme (AgCA) showed kinetic parameters for the CO(2) hydration reaction comparable with those of the human erythrocytes

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