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Merck

P2307

Sigma-Aldrich

Polyvinylpyrrolidone

suitable for plant cell culture, average mol wt 10,000

Sinónimos:

PVP, Polyvidone, Povidone

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About This Item

Fórmula lineal:
(C6H9NO)n
Número de CAS:
Número MDL:
Código UNSPSC:
12352207
ID de la sustancia en PubChem:
NACRES:
NA.71

formulario

powder

Nivel de calidad

mol peso

average mol wt 10,000

técnicas

cell culture | plant: suitable

número de viscosidad

12-18(lit.)

cadena SMILES

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

Clave InChI

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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Aplicación


  • Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats.: This study presents the development of a microneedle patch containing Polyvinylpyrrolidone (PVP), which enhances the delivery of anti-obesity medication, showcasing PVP′s utility in pharmaceutical formulations to improve drug solubility and efficacy (Wang H et al., 2024).

  • Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This research demonstrates the role of PVP, as a stabilizer and regulator in the synthesis of a nanodrug cocktail, indicating its critical function in nanomedicine for targeting and treating cancer effectively, thereby optimizing therapeutic outcomes (Wang C et al., 2024).

  • Biochemical parameters, oxidative stress biomarkers, and anatomopathological changes in Wistar rats treated with 3′-demethoxy-6-O-demethylisoguaiacin and norisoguaiacin.: The study utilizes PVP in biomedical applications, particularly in enhancing the solubility and bioavailability of specific bioactive compounds for therapeutic purposes (Flores Jimenez NG et al., 2024).

  • A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats.: Highlighting PVP′s importance in creating water-soluble drug formulations that facilitate the intravenous delivery of hydrophobic substances, this study explores its application in improving drug delivery systems (Rassu G et al., 2024).

  • Activation of the PPAR gamma/NF-kB pathway by A-MPDA@Fe(3)O(4)@PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury.: This innovative study employs PVP to stabilize nanoparticle systems that actively participate in reducing oxidative stress, illustrating PVP′s potential in therapeutic interventions (Mo D et al., 2024).

Otras notas

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Obesity is a major risk for diabetes. Brown adipose tissue (BAT) mediates production of heat while white adipose tissue (WAT) function in the storage of fat. Roles of BAT in the treatment of obesity and related disorders warrants more investigation.
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Journal of clinical microbiology, 46(7), 2252-2262 (2008-05-02)
In the present study, we analyzed genetic variation in Cryptosporidium species from humans (n = 62) with clinical cryptosporidiosis in South Australia. Sequence variation was assessed in regions within the small subunit of nuclear rRNA (p-SSU), the 70-kDa heat shock
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American journal of physiology. Endocrinology and metabolism, 294(5), E853-E860 (2008-03-13)
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for patients with comorbid diabetes and depression. Clinical case studies in diabetic patients, however, suggest that SSRI therapy may exacerbate hypoglycemia. We hypothesized that SSRIs might increase the risk of hypoglycemia by
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Journal of photochemistry and photobiology. B, Biology, 120, 74-81 (2013-03-08)
Photodynamic therapy (PDT) is a local tumour treatment accepted for a number of indications. PDT operates via the cellular stress response through the production of reactive oxygen species and subsequent cellular damage, resulting in cell death. Although PDT-induced signalling and

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