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P1150000

Phenylalanine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

L-Phenylalanine, (S)-2-Amino-3-phenylpropionic acid

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About This Item

Fórmula lineal:
C6H5CH2CH(NH2)CO2H
Número de CAS:
63-91-2
Peso molecular:
165.19
Beilstein:
1910408
Número MDL:
MFCD00064227
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329820075
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

phenylalanine

fabricante / nombre comercial

EDQM

mp

270-275 °C (dec.) (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

Clave InChI

COLNVLDHVKWLRT-QMMMGPOBSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Phenylalanine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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L0375000

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USP

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1485125

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Aspartame impurity A European Pharmacopoeia (EP) Reference Standard

A1321000

Aspartame impurity A

L-Phenylalanine for biochemistry

Millipore

1.07256

L-Phenylalanine

Serine European Pharmacopoeia (EP) Reference Standard

S0450000

Serine

USP

USP

1485136

Oxybutynin Related Compound C

L-Phenylalanine 99%, natural, FCC, FG

Sigma-Aldrich

W358512

L-Phenylalanine

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Cancer research, 74(20), 5891-5902 (2014-08-29)
The discovery of somatic mutations in EGFR and development of EGFR tyrosine kinase inhibitors (TKI) have revolutionized treatment for lung cancer. However, resistance to TKIs emerges in almost all patients and currently no effective treatment is available. Here, we show
F J van Spronsen et al.
Journal of inherited metabolic disease, 32(1), 46-51 (2009-02-05)
In phenylketonuria, mental retardation is prevented by a diet that severely restricts natural protein and is supplemented with a phenylalanine-free amino acid mixture. The result is an almost normal outcome, although some neuropsychological disturbances remain. The pathology underlying cognitive dysfunction
Minghua Tang et al.
The American journal of clinical nutrition, 99(4), 891-898 (2014-01-17)
Data on the protein requirements of elderly adults are limited, because it is impractical to conduct repeated nitrogen balance protocols in these vulnerable humans. This study was designed to determine the dietary protein requirement of elderly women by using the
Julia Albrecht et al.
Neuroscience and biobehavioral reviews, 33(3), 414-421 (2008-11-29)
Although pathogenesis of phenylketonuria is not completely understood, a low phenylalanine diet is effective to prevent severe neurological impairment, mental retardation and behavioural difficulties. Treatment recommendations heavily rely on neuropsychological research; however, single study results are ambiguous, what is reflected
John J Mitchell et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 13(8), 697-707 (2011-05-11)
Phenylalanine hydroxylase deficiency is an autosomal recessive disorder that results in intolerance to the dietary intake of the essential amino acid phenylalanine. It occurs in approximately 1:15,000 individuals. Deficiency of this enzyme produces a spectrum of disorders including classic phenylketonuria
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