Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

D1000000

Dibenzosuberone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

5-Dibenzosuberone, 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one, Dibenzocycloheptadienone

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C15H12O
Número de CAS:
1210-35-1
Peso molecular:
208.26
Beilstein:
1454355
Número MDL:
MFCD00003587
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329798658
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

nortriptyline, amitriptyline

fabricante / nombre comercial

EDQM

índice de refracción

n20/D 1.6332 (lit.)

bp

148 °C/0.3 mmHg (lit.)

mp

32-34 °C (lit.)

densidad

1.156 g/mL at 25 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

formato

neat

cadena SMILES

O=C1c2ccccc2CCc3ccccc13

InChI

1S/C15H12O/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8H,9-10H2

Clave InChI

BMVWCPGVLSILMU-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Dibenzosuberone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

1029002

Amitriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard

1474005

Nortriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard

N1280000

Nortriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1384

Amitriptyline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

Y0000563

Amitriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard

Y0001296

Nortriptyline for system suitability, European Pharmacopoeia (EP) Reference Standard

1029013

Amitriptyline Related Compound A, United States Pharmacopeia (USP) Reference Standard

1029024

Amitriptyline Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR1776

Amitriptyline Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP269

Nortriptyline hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP016

Amitriptyline hydrochloride, British Pharmacopoeia (BP) Reference Standard

BP858

Dibenzosuberone, British Pharmacopoeia (BP) Reference Standard

PHR3216

Nortriptyline Hydrochloride, pharmaceutical secondary standard, certified reference material

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

235.4 °F - closed cup

Punto de inflamabilidad (°C)

113 °C - closed cup

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Stefan Fischer et al.
Journal of medicinal chemistry, 56(1), 241-253 (2012-12-29)
p38α mitogen-activated protein (MAP) kinase is a main target in drug research concerning inflammatory diseases. Nevertheless, no inhibitor of p38α MAP kinase has been introduced to the market. This might be attributed to the fact that there is no inhibitor
Solveigh C Koeberle et al.
Journal of medicinal chemistry, 55(12), 5868-5877 (2012-06-09)
Synthesis, biological testing, structure-activity relationships (SARs), and selectivity of novel disubstituted dibenzosuberone derivatives as p38 MAP kinase inhibitors are described. Hydrophilic moieties were introduced at the 7-, 8-, and 9-position of the 2-phenylamino-dibenzosuberones, improving physicochemical properties as well as potency.
Sonja Merkas et al.
Molecules (Basel, Switzerland), 10(12), 1429-1437 (2007-11-17)
Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared: 3,7-dibromo-5-(dimethylaminoethyl- oxyimino)-10,11-dihydro-5H-dibenzo[a,d]cyclohepta-1,4-diene (1), 3,7-dibromo-5-(3- dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (2) and 1,7- dibromo-5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo-[a,d]-cycloheptene (3). These compounds are potential tricyclic antidepressants (TCAs), which are still the most frequently prescribed antidepressants in many
S P Dixon et al.
Pharmeuropa scientific notes, 2005(1), 15-20 (2007-08-11)
An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.
S Zbaida et al.
Biopharmaceutics & drug disposition, 11(1), 39-51 (1990-01-01)
Reactions of trans-stilbene, cis-stilbene, 5H-dibenzo [a,d] cyclo-heptene 5-one and 5H-dibenz [b,f] azepine (iminostilbene) with Fenton reagent [Fe (II)/H2O2] clearly simulate their hepatic metabolism. Expoxidation on the corresponding ethylenic linkage was found to be a common pathway of these compounds. Epoxides

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico