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D0720800

Dexchlorpheniramine maleate

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

S-(+)-Chlorpheniramine maleate salt, (S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate salt

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About This Item

Fórmula empírica (notación de Hill):
C16H19ClN2 · C4H4O4
Número de CAS:
2438-32-6
Peso molecular:
390.86
Número MDL:
MFCD00079046
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329798631
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

dexchlorpheniramine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

[H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1

Clave InChI

DBAKFASWICGISY-DASCVMRKSA-N

Información sobre el gen

human ... HRH1(3269)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Dexchlorpheniramine maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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O Cáceres Calle et al.
Allergologia et immunopathologia, 32(5), 306-309 (2004-10-01)
Dexchlorpheniramine (DH) is a classical or first generation antihistamine belonging to the ethanolamine group. Adverse effects related to these antihistamines are frequent, but the hypersensitivity reactions described in the literature since 1940 are exceptional. We report the case of a
Anaphylaxis induced by Anisakis.
J Antón et al.
Allergologia et immunopathologia, 36(1), 53-55 (2008-02-12)
Nilton S Viana et al.
Farmaco (Societa chimica italiana : 1989), 60(11-12), 900-905 (2005-10-18)
Formulation excipients can frequently affect the drug analysis in pharmaceuticals yielding background interference by ultraviolet spectrophotometry. Sample separation procedures to diminish such interferences are usually recommended as sample pre-treatment, however it can be difficult to eliminate them and they can
José R Villada et al.
Journal of cataract and refractive surgery, 31(3), 620-621 (2005-04-07)
We report a severe anaphylactic reaction that occurred about 5 minutes after 1.0 mg of cefuroxime was injected into the anterior chamber after routine phacoemulsification and intraocular lens implantation. The patient was known to be allergic to penicillin. Immediate action
Eef L Theunissen et al.
British journal of clinical pharmacology, 61(1), 79-86 (2006-01-05)
Previous studies have demonstrated that the antihistamines mequitazine, cetirizine and dexchlorpheniramine produce mild sedation after single doses. It is unknown, however, whether acute sedation persists after repeated dosing. Therefore, this study assessed the effects of repeated dosing of these antihistamines
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