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Merck

BCR157

Benz[a]acridine

BCR®, certified reference material

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About This Item

Fórmula empírica (notación de Hill):
C17H11N
Número de CAS:
Peso molecular:
229.28
Beilstein:
9262
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material

Agency

BCR®

fabricante / nombre comercial

JRC

técnicas

HPLC: suitable
gas chromatography (GC): suitable

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

c1ccc2nc3ccc4ccccc4c3cc2c1

InChI

1S/C17H11N/c1-3-7-14-12(5-1)9-10-17-15(14)11-13-6-2-4-8-16(13)18-17/h1-11H

Clave InChI

JEGZRTMZYUDVBF-UHFFFAOYSA-N

Nota de análisis

For more information please see:
BCR157

Información legal

BCR is a registered trademark of European Commission

Pictogramas

Exclamation markEnvironment

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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R P Deutsch-Wenzel et al.
Cancer letters, 20(1), 97-101 (1983-08-01)
Using a beeswax/tricaprylin mixture as vehicle, three doses each of acridine, benz[a]acridine (BaAC), benz[c]acridine (BcAC), dibenz[a,h]-acridine (DBa,hAC) and dibenz[a,j]acridine (DBa,jAC) were injected into the lungs of 35 female Osborne-Mendel rats per group. To compare the carcinogenic potency of the heterocycles
J Jacob et al.
Cancer letters, 16(3), 297-306 (1982-09-01)
The metabolism of benz[a]- and benz[c]acridine by liver and lung microsomes from untreated, phenobarbital (PB)-treated and benzo[k]fluoranthene (BkF)-treated rats has been studied by gas chromatography/mass spectrometry (GC/MS). Epoxidation and hydrolysis of the epoxides to dihydrodiols were found to be the
J Molnár et al.
Anticancer research, 13(4), 1019-1025 (1993-07-01)
This review summarizes our experiments which are investigating the relationship between the structure and activity of mainly phenothiazines, benzo[a]phenothiazines and benz[c]acridines. Phenothiazines had potent antiplasmid and antibacterial activities, but induced weak antimicrobial activity in vivo. Their antiplasmid activity seemed to
N Motohashi et al.
Anticancer research, 12(4), 1207-1210 (1992-07-01)
The abilities of 14 phenothiazines, 8 benzo[a]phenothiazines and 12 benz[c]acridines to induce an antibacterial effect against Escherichia coli K12 were compared. Several phenothiazines, which showed antiplasmid activity, displayed the most potent antibacterial activity. All benz[c]acridine derivatives were moderately antibacterial, whereas
Benz[a]acridine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 32, 123-127 (1983-12-01)

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