SCT094

BioTracker NIR FolateReceptor Live Cell Dye

• Sinónimos: BioTracker NIR FolateReceptor Live Cell Dye
• Código UNSPSC: 12352207
• NACRES: NA.47

Propiedades

• formulario: lyophilized
• mol peso: calculated mol wt 1196.30
• envase: pkg of 1 mg
• fabricante / nombre comercial: Millipore
• condiciones de almacenamiento: protect from light
• modo de crecimiento: N/A
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Folate receptors (FRs) are membrane bound surface proteins involved in folic acid uptake. FRs are frequently overexpressed in a large number of solid tumors including cancers of the ovary, breast and lung. FRs are attractive candidates for cancer imaging and targeted therapies.BioTracker NIR Folate Receptor Live Cell Dye is a near-infrared (NIR) fluorescent probe for the detection of folate receptors in vivo. This probe exhibits very low background fluorescence and high tumor-to-background ratio in FR-expressing tumor-bearing mice within 30 min (1).Reference:1. Numasawa, Koji, et al. "A Fluorescent Probe for Rapid, High‐Contrast Visualization of Folate‐Receptor‐Expressing Tumors In Vivo." Angewandte Chemie International Edition 59.15 (2020): 6015-6020.

Aplicación

Purity ≥ 95% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

Características y beneficios

Near-Infrared probe for detection and visualization of folate receptors in vivo.

Forma física

Lyophilized. Green solid.

Almacenamiento y estabilidad

Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable