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RPTMAG-86K

Millipore

MILLIPLEX® Rat Pituitary Magnetic Bead Panel - Endocrine Multiplex Assay

The analytes available for this multiplex kit are: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH.

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About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000

Nivel de calidad

200

reactividad de especies

rat

fabricante / nombre comercial

Milliplex®

assay range

accuracy: 75%
(GH)
accuracy: 88%
(ACTH)
accuracy: 89%
(LH)
accuracy: 90%
(TSH)
sensitivity: 0.38 pg/mL
(BDNF)
sensitivity: 0.87 pg/mL
(TSH)
sensitivity: 1.95 pg/mL
(ACTH)
sensitivity: 3.28 pg/mL
(LH)
sensitivity: 4.64 pg/mL
(Prolactin)
sensitivity: 6.50 pg/mL
(GH)
sensitivity: 7.62 pg/mL
(FSH)
standard curve range: 16-50,000 pg/mL
(GH, Prolactin)
standard curve range: 3.2-10,000 pg/mL
(ACTH, BDNF, LH, TSH)
standard curve range: 32-100,000 pg/mL
(FSH)
inter-assay cv: <20%
intra-assay cv: <10%

técnicas

multiplexing: suitable

método de detección

fluorometric (Luminex xMAP)

Condiciones de envío

wet ice

Categorías relacionadas

Descripción general

Called the “master gland” because it controls many other endocrine glands, the pituitary secretes several key hormones that play important roles in the regulation of metabolism, growth, and reproduction. Piuitary hormones are responsible for the stimulation of the adrenal gland (ACTH), thyroid gland (TSH), ovaries and testes (FSH, LH) and breast milk production (prolactin), as well as blood pressure and the amount of water excreted by the kidneys. Through its connection with the pituitary, the hypothalamus modulates endocrine function by detecting hormone levels. Brain-Derived Neurotrophic Factor (BDNF) is a member of NGF family of neurotrophic factors which are required for differentiation and survival of specific neuronal sub-populations.

MILLIPLEX® Rat Pituitary Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in rat serum or plasma samples, rat tissue extract, or cell/tissue culture supernatant samples: Growth Hormone (GH), Thyroid-Stimulating Hormone (TSH), Adrenocorticotropic Hormone (ACTH), Luteinizing Hormone (LH), Prolactin, Follicle-Stimulating Hormone (FSH), and Brain-Derived Neurotrophic Factor (BDNF). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Endocrine

Aplicación

  • Analytes: Adrenocorticotropic Hormone (ACTH), Brain-Derived Neurotrophic Factor (BDNF), Follicle-Stimulating Hormone (FSH), Growth Hormone (GH), Luteinizing Hormone (LH), Prolactin, Thyroid-Stimulating Hormone (TSH)
  • Recommended Sample Type: Rat serum, plasma, cell/tissue culture supernatants or lysates
  • Recommended Sample Dilution: 25 μL per well 1:3 diluted serum or plasma; cell/tissue culture samples may require dilution in an appropriate control medium.
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Endocrine
  • Research Subcategory: Metabolism

Características y beneficios

Design your multiplex kit by choosing available analytes within this panel.

Información legal

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Pictogramas

Skull and crossbonesEnvironment
GHS06,GHS09

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Ivraym B Barsoum et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(7), 2657-2666 (2013-04-10)
Testes contain two distinct Leydig cell populations during development: fetal and adult Leydig cells (FLCs and ALCs, respectively). ALCs are not derived from FLCs, and it is unknown whether these two populations share common progenitors. We discovered that hedgehog (Hh)
Global but not gonadotrope-specific disruption of Bmal1 abolishes the luteinizing hormone surge without affecting ovulation.
Chu, A; Zhu, L; Blum, ID; Mai, O; Leliavski, A; Fahrenkrug, J; Oster, H; Boehm, U; Storch, KF
Endocrinology null
Vivi F H Jensen et al.
Scientific reports, 10(1), 5609-5609 (2020-03-30)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and
Renee N Sadowski et al.
Neurotoxicology and teratology, 42, 17-24 (2014-01-21)
Previous work has shown that exposure to bisphenol A (BPA) can affect anxiety behavior. However, no studies have examined whether administration of this endocrine disruptor during the perinatal period has the potential to induce alterations in cognitive behavior in both
Vanessa D Sherk et al.
Medicine and science in sports and exercise, 51(12), 2465-2473 (2019-07-06)
The purpose of this study was to determine whether obesity and/or exercise training alters weight regain and musculoskeletal health after ovariectomy (OVX). Female rats were fed high-fat diet (HFD) to reveal obesity-prone (OP) and obesity-resistant (OR) phenotypes. The OP and
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