MABN139

Anti-mGluR5 Antibody, clone 11D9.1

clone 11D9.1, from mouse

• Sinónimos: Metabotropic glutamate receptor 5, mGluR5
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 11D9.1, monoclonal
• reactividad de especies: human, rat
• técnicas: immunohistochemistry: suitable; western blot: suitable
• isotipo: IgG2bκ
• Nº de acceso NCBI: NP_000833
• Nº de acceso UniProt: P41594
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GRM5(2915)

Descripción

Descripción general

Metabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

Inmunógeno

GST-tagged recombinant protein corresponding to human mGluR5.

Aplicación

Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.

Calidad

Evaluated by Western Blotting in rat brain micropreparation tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected mGluR5 in 10 µg of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.

Descripción de destino

~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).

Forma física

Format: Purified

Nota de análisis

Control
Rat brain micropreparation tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable