MABF142C

Anti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody

clone 1A8, from rat, PE-Cy7

• Sinónimos: Lymphocyte antigen 6G (Ly-6G), Ly-6G.1, Ly-6G
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rat
• Nivel de calidad: 100
• conjugado: PE-Cy7
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: 1A8, monoclonal
• reactividad de especies: mouse
• envase: antibody small pack of 25 μg
• técnicas: flow cytometry: suitable
• isotipo: IgG2aκ
• Nº de acceso UniProt: P35461
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Ly6G(546644)

Descripción

Descripción general

The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151: 2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Inmunógeno

Immunogen information for this antibody is proprietary information.

Aplicación

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Anti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody is validated for use in Flow Cytometry for the detection of Ly-6G.

Calidad

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected Ly-6G in one million C57Bl/6 bone marrow cells.

Forma física

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

Purified by size-exclusion chromatography

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Otras notas

Concentration: Please refer to lot specific datasheet.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable