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MABE167

Sigma-Aldrich

Anti-SNAI1 Antibody, clone 10H4.1

clone 10H4.1, from mouse

Sinónimos:

Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

10H4.1, monoclonal

reactividad de especies

human, rat, mouse

técnicas

immunohistochemistry: suitable
western blot: suitable

isotipo

IgMκ

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... SNAI1(6615)

Descripción general

SNAI1, also known as Snail homolog 1, is a transcription factor that down regulates the expression of ectodermal genes within the mesoderm and is thought to be essential for mesoderm formation in the developing embryo. SNAI1 is expressed in the kidney and in mesenchymal and epithelial cell lines. Mutations in SNAI1 have been associated with tumors.

Inmunógeno

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of Human SNAIL1.

Aplicación

Anti-SNAI1 Antibody, clone 10H4.1 is a highly specific mouse monoclonal antibody, that targets Zinc Finger Protein & has been tested in western blotting & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected SNAIL1 in 10 µg of human and mouse kidney tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAIL1 in human kidney section and human tonsil section tissues.

Calidad

Evaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected SNAIL1 in 10 µg of rat kidney tissue lysate.

Descripción de destino

~29 kDa observed

Forma física

Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hideki Yamasaki et al.
Genes to cells : devoted to molecular & cellular mechanisms, 10(5), 455-464 (2005-04-20)
Snail, a DNA-binding zinc finger protein, functions as a transcriptional repressor for genes including E-cadherin during development and the acquisition of tumor cell invasiveness. Human Snail is a 264-amino acid nuclear protein with an amino-terminal basic amino acid-rich domain (SNAG
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PLoS genetics, 11(7), e1005324-e1005324 (2015-07-07)
Vascular branching morphogenesis is activated and maintained by several signaling pathways. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) signaling is largely presented in arteries, and VEGFR3 signaling is in veins and capillaries. Recent reports have documented that Snail

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