MABC282

Anti-BAG3 Antibody, clone AC-1

clone AC-1, from mouse

• Sinónimos: BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: AC-1, monoclonal
• reactividad de especies: human
• técnicas: immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_004272
• Nº de acceso UniProt: O95817
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... BAG3(9531)

Descripción

Descripción general

Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH.

Aplicación

Detect BAG3 using this Anti-BAG3 Antibody, clone AC-1 validated for use in Immunoprecipitation, IHC(P).

Calidad

Evaluated by Immunoprecipitation in HeLa cell lysate.

Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated BAG3 from HeLa cell lysate.

Descripción de destino

~62 kDa observed

Forma física

Format: Purified

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable