MAB3786

Anti-APC Antibody, CT, clone C-APC 28.9

clone C-APC 28.9, Chemicon^®, from mouse

• Sinónimos: Adenomatous Polyposis Coli Protein
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: C-APC 28.9, monoclonal
• reactividad de especies: human, mouse
• envase: antibody small pack of 25 μg
• fabricante / nombre comercial: Chemicon^®
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NM_000038.3
• Nº de acceso UniProt: P25054
• Condiciones de envío: ambient
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... APC(324) ; mouse ... Apc(11789)

Descripción

Descripción general

The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations.

Especificidad

Recognizes human APC, molecular weight is approximately 310kDa.

Inmunógeno

Epitope: C-terminus

Human APC C-terminal fusion with MBP (maltose binding protein).

Aplicación

Anti-APC Antibody, C-terminus, clone C-APC 28.9 is a Mouse Monoclonal Antibody for detection of APC also known as Adenomatous Polyposis Coli Protein & has been validated in IF, IP, WB & IHC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Western blot

Immunohistochemistry (Frozen sections)

Immunofluorescence

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Calidad

Tested

Forma física

Format: Purified

Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.

Almacenamiento y estabilidad

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Nota de análisis

Control
POSITIVE CONTROL: colon cell line HCT116

Otras notas

feature_concentration_valuePlease refer to lot specific datasheet.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable