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Key Documents

MAB2251

Sigma-Aldrich

Anti-Integrin β1 Antibody, clone B3B11

clone B3B11, Chemicon®, from mouse

Sinónimos:

CD29

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

B3B11, monoclonal

reactividad de especies

human

fabricante / nombre comercial

Chemicon®

técnicas

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ITGB1(3688)

Especificidad

Reacts with the human integrin beta1 subunit. Specificity verified by preclearing of beta1in immunoprecipitation, flow cytometry on transfectant cells displaying human beta1 integrin, and reactivity with purified beta1. Epitope lies within the same cluster recognized by MAB2250, and within amino acids 648-670 of the mature beta1 integrin chain.1

Inmunógeno

source is Jurkat T-leukemic cell line

Aplicación

Anti-Integrin β1 Antibody, clone B3B11 is an antibody against Integrin β1 for use in FC, IP, WB, FUNC, IH.
Immunoprecipitation

Immunohistochemistry on frozen sections

Flow cytometry

Immunoblotting (Western)

Stimulates adhesion of cells to extracellular matrix proteins1

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Forma física

Format: Purified
Purified immunoglobulin from Protein A Sepharose chromatography. Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% sodium azide.

Almacenamiento y estabilidad

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sarah L Londrigan et al.
Journal of virology, 77(17), 9486-9501 (2003-08-14)
Rotaviruses utilize integrins during virus-cell interactions that lead to infection. Cell binding and infection by simian rotavirus SA11 were inhibited by antibodies (Abs) to the inserted (I) domain of the alpha2 integrin subunit. To determine directly which integrins or other
Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase.
Satpathy, M; Cao, L; Pincheira, R; Emerson, R; Bigsby, R; Nakshatri, H; Matei, D
Cancer Research null
Interactions between collagen IV and collagen-binding integrins in renal cell repair after sublethal injury.
Nony, P A and Schnellmann, R G
Molecular Pharmacology, 60, 1226-1234 (2001)
Ewa Pocheć et al.
Analytical cellular pathology (Amsterdam), 2015, 324980-324980 (2015-09-05)
N-glycosylation plays an important role in the majority of physiological and pathological processes occurring in the immune system. Alteration of the type and abundance of glycans is an element of lymphocyte differentiation; it is also common in the development of
Alison McDowall et al.
The Journal of clinical investigation, 111(1), 51-60 (2003-01-04)
The adhesion receptors known as integrins perform key functions for hematopoietic cells. The platelet integrin alphaIIbbeta3 is critical in hemostasis, and the beta1 and beta2 integrins on leukocytes have many roles in cell-mediated immunity. Mutations in the beta2 subunit lead

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