MAB1961
Anti-Integrin αVβ5 Antibody, clone P1F6
clone P1F6, Chemicon®, from mouse
Sinónimos:
Anti-CD51, Anti-MSK8, Anti-VNRA, Anti-VTNR
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
mouse
Nivel de calidad
forma del anticuerpo
purified immunoglobulin
tipo de anticuerpo
primary antibodies
clon
P1F6, monoclonal
reactividad de especies
human, chicken
fabricante / nombre comercial
Chemicon®
técnicas
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotipo
IgG1
idoneidad
not suitable for immunohistochemistry (Paraffin)
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... ITGAV(3685)
Descripción general
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Especificidad
Reacts with the human integrin alphaVbeta5.
Inmunógeno
Human UCLA P3 cells (lung carcinoma)
Aplicación
Inhibition of attachment of HT29 cells to vitronectin: >1:1,000
Inhibition of attachment of carcinoma and melanoma cells to vitronectin.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. (Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.)
Immunocytochemistry: 1:1500. For use on human carcinomas, normal epithelium and keratinocytes (Acetone Fixed Only).
Immunoprecipitation
FACS
EIA
Optimal working dilutions must be determined by the end user.
Inhibition of attachment of carcinoma and melanoma cells to vitronectin.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. (Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.)
Immunocytochemistry: 1:1500. For use on human carcinomas, normal epithelium and keratinocytes (Acetone Fixed Only).
Immunoprecipitation
FACS
EIA
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
This Anti-Integrin αVβ5 Antibody, clone P1F6 is validated for use in FC, IC, IH, IP, FUNC for the detection of Integrin αVβ5.
Forma física
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified
Almacenamiento y estabilidad
Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Nota de análisis
Control
Epithelium, keratinocytes
Epithelium, keratinocytes
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
¿No encuentra el producto adecuado?
Pruebe nuestro Herramienta de selección de productos.
Opcional
Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Dendritic cell activation by sensing Mycobacterium tuberculosis-induced apoptotic neutrophils via DC-SIGN.
Hedlund S, Persson A, Vujic A, Che KF, Stendahl O, Larsson M
Human immunology null
Integrins in metastatic adenoid cystic carcinoma.
A J Lyons, J Jones X-T Xie, A J Lyons, J Jones X-T Xie, A J Lyons, J Jones X-T Xie
International Journal of Oral and Maxillofacial Surgery null
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Aldrian, S; Trautinger, F; Frohlich, I; Berger, W; Micksche, M; Kindas-Mugge, I
Cell Stress & Chaperones null
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation.
Sanlioglu, S; Benson, PK; Yang, J; Atkinson, EM; Reynolds, T; Engelhardt, JF
Journal of virology null
Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA.
Kim, J; Nam, HY; Kim, TI; Kim, PH; Ryu, J; Yun, CO; Kim, SW
Biomaterials null
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico