MAB1645

Anti-Dystrophin Antibody

CHEMICON^®, mouse monoclonal, 1808

• Sinónimos: Anti-BMD, Anti-CMD3B, Anti-DXS142, Anti-DXS164, Anti-DXS206, Anti-DXS230, Anti-DXS239, Anti-DXS268, Anti-DXS269, Anti-DXS270, Anti-DXS272, Anti-MRX85
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• Nombre del producto: Anti-Dystrophin Antibody, clone 1808, clone 1808, Chemicon^®, from mouse
• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: 1808, monoclonal
• reactividad de especies: chicken, mouse, rat, human
• fabricante / nombre comercial: Chemicon^®
• técnicas: immunohistochemistry: suitable; western blot: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NM_000109.2; NM_004006.1; NM_004007.1; NM_004009.2; NM_004010.2; NM_004011.2; NM_004012.2; NM_004013.1; NM_004014.1; NM_004015.1; NM_004016.1; NM_004017.1; NM_004018.1; NM_004019.2; NM_004020.1; NM_004021.1; NM_004022.1; NM_004023.1
• Nº de acceso UniProt: P11532
• Condiciones de envío: dry ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... DMD(1756)

Descripción

Especificidad

By Western blot MAB1645 recognizes a single protein having a relative molecular weight of 300 kD. Reacts to mammalian skeletal muscle dystrophin. Shows no staining of mdx mouse muscle. Labels normal human muscle but not Duchenne muscle.

STAINING PATTERN:

On cryostat sections of normal mouse diaphragm MAB1645 gives strong immunofluorescence staining of the entire sarcolemma, with particularly strong staining of neuromuscular junctions.

SPECIES REACTIVITY:

Labels skeletal muscle from rat, chicken and Xenopus laevis. Labels cardiac muscle from rat and normal, but not mdx, mouse. Also labels smooth muscle from chicken gizzard.

Inmunógeno

Peripheral membrane proteins extracted from Torpedo postsynaptic membranes.

Aplicación

Anti-Dystrophin Antibody, clone 1808 detects level of Dystrophin & has been published & validated for use in WB, IH.

Western blot

Immunohistochemistry

Optimal working dilutions must be determined by the end user.

Forma física

Format: Purified

Liquid in 0.02 M phosphate buffer (pH 7.6), 250 mM NaCl with 0.1% sodium azide.

Almacenamiento y estabilidad

Maintain at -20ºC for up to 12 months in convenient aliquots. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable