Saltar al contenido
Merck
Todas las fotos(2)

Key Documents

MAB11041

Sigma-Aldrich

Anti-Serotonin receptor 1A Antibody, clone 19A9.2

clone 19A9.2, from mouse

Sinónimos:

5-hydroxytryptamine (serotonin) receptor 1A, 5-hydroxytryptamine receptor 1A, guanine nucleotide-binding regulatory protein-coupled receptor, Serotonin receptor 1A, G protein coupled receptor, 5-HT1a receptor

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

19A9.2, monoclonal

reactividad de especies

human, rat

técnicas

immunohistochemistry: suitable
western blot: suitable

isotipo

IgMκ

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... HTR1A(3350)
rat ... Htr1A(24473)

Descripción general

Serotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.

Inmunógeno

KLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.

Aplicación

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.
Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.
Research Category
Neuroscience
Research Sub Category
Signaling Neuroscience

Calidad

Evaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.

Descripción de destino

~40 kDa observed. The calculated molecular weight is 46 kDa

Forma física

Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Rat brain tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Laura García-Durán et al.
International journal of molecular sciences, 22(19) (2021-10-14)
Selective 5-HT reuptake inhibitor antidepressants (SSRIs) are the first choice in major depressive disorder (MDD), but 50% of affected patients do not show improvement. Galanin(1-15) [GAL(1-15)] enhanced Fluoxetine antidepressant-like effects in an animal model of depression, the olfactory bulbectomy (OBX);
Elenia Cinelli et al.
The European journal of neuroscience, 52(8), 3903-3917 (2020-05-08)
In mammals, 5-HTexcitatory respiratory effects imply 5-HT1A receptor-mediated disinhibition of pre-Bötzinger complex neurons. In the lamprey, 5-HT1A receptors are involved in the neural control of locomotion, but their role in the respiratory regulation, particularly at the level of the putative

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico